Silently, without fanfare, an invisible battle takes place every day in your body. The main heroes of this story are NK cells, the natural killers of the immune system, which form the first line of defense against intruders.
What are NK cells?
NK cells (Natural Killer cells) are white blood cells and a key component of innate immunity. Unlike other immune cells, they do not need “training” or prior encounter with the enemy. They are able to immediately recognize and destroy abnormal cells in the body.
Their unique feature is their ability to identify cells that try to “camouflage” themselves to escape the immune system. This property makes NK cells extremely effective guardians that constantly monitor your body.
How do NK cells work?
Imagine NK cells as elite soldiers patrolling your body. When they encounter a suspicious cell (e.g., infected with a virus or abnormally modified), the NK cell attacks it and initiates a process called “cell death kiss.”
During this process, the NK cell releases cytotoxic substances (perforins and granzymes) that penetrate the target cell's membrane and trigger its programmed cell death. In simple terms, NK cells force dangerous cells to “commit suicide.”
What influences NK cell activity?
NK cell activity is not constant; it can vary depending on many factors:
- Stress and NK cells
Chronic stress significantly reduces NK cell activity. Studies show that people exposed to prolonged stress have up to 50% lower NK cell activity.
- Sleep as a regenerator
During deep sleep, NK cells regenerate and “recharge” for their next activity. A lack of quality sleep can reduce their number and activity.
- Diet, fuel for immunity
A diet rich in antioxidants, vitamins, and minerals promotes optimal NK cell function. Research shows that vitamin D, zinc, and selenium are particularly important for NK cell activity.
- Physical exercise strengthens the immune system
Regular, moderate physical activity can increase the number and activity of NK cells. However, overly intense training can have the opposite effect.
Japanese research on NK cells
Japanese researchers are at the forefront of global research on NK cells. For more than three decades, they have been studying how these cells work and the factors that can increase their activity.
One of the most interesting discoveries made by Japanese scientists concerns the influence of certain polysaccharides on NK cell activity. Research by Dr. Mamdooh Ghoneum has shown that specific compounds extracted from shiitake mushrooms and rice bran can increase NK cell activity by up to 300%.
These discoveries have led to the development of natural immunomodulators that help maintain optimal NK cell activity.
Practical tips for strengthening NK cells
1. Get enough sleep – 7 to 8 hours a day at regular times
2. Reduce stress – practice meditation, yoga, or deep breathing
3. Include antioxidant-rich foods in your diet – colourful fruits and vegetables
4. Maintain healthy vitamin D levels – get some sun or take supplements
5. Get moderate exercise – ideally 30 minutes a day
6. Limit alcohol consumption – excessive drinking significantly reduces NK cell activity
When you need an extra boost
During periods of increased stress or when the immune system is facing difficult challenges, you can turn to natural remedies. Among the proven substances that promote NK cell activity is beta-glucan, found in shiitake and oyster mushrooms.
For comprehensive immune support, ImunoBran is also worth considering. This is a natural supplement developed by Japanese researchers that contains a patented ingredient called MGN-3 Arabinoxylan. This unique polysaccharide, obtained through a special enzymatic process from rice bran and shiitake mushrooms, has been proven to stimulate NK cell activity, thereby contributing to overall immune balance.
Conclusion
NK cells are a fascinating part of our immune system: they are tireless guardians that protect us against the development of many diseases. Their activity is directly influenced by our lifestyle, diet, and overall approach to health.