Do you know anything about your immune system and especially about NK cells?
The Really Healthy Company
The role of natural killer (NK) cells.
Mediation of the Immune System
The immune system is not only our defence against the environment, it is also essential to maintain the integrity and function of the body. It also provides intelligence in the day-to-day housekeeping that is essential for us to remain alive.
Our primary immune response is mediated by lymphocytes (white blood cells), macrophages, mast cells, hormones and other messengers circulating in the blood and lymphatic systems.
NK cells are a type of lymphocyte, those white blood cells that are part of the innate immune system (they do not have a memory of infection but rather act on pure instinct at the moment). This instinctive branch of our immune reaction is the first line of defence against the environment and foreign invaders (like viruses, bacteria, parasites and toxins), including the severe acute respiratory syndrome (SARS), as well as tumour cells. NK cells are the most aggressive of our immune system's soldiers. The motto of these microscopic Caped Crusaders is "seek-and-destroy."
NK cells are pre-programmed to seek out and destroy infected and cancerous cells. However, they do not destroy indiscriminately. They are able to intelligently scan cells that they come in contact with, much like scanning a barcode, and they will very specifically destroy only faulty or infected cells.
Research has shown that patients with compromised (or overburdened) immune systems, or those that have undergone immunosuppressive therapy (radiation and chemotherapy), have decreased NK cell activity. In fact, in patients with metastatic disease, the survival time directly correlates with the level of NK cell activity. This NK activity is also severely reduced in autoimmune disease and chronic fatigue syndrome.
ImunoBran and NK cells
Dr M. Ghoneum, an immunologist at the University of California, LA. has been one of the primary ImunoBran researchers and has spent many years investigating its immunomodulatory effect. He stated: "I studied for almost ten years what makes NK cells weak and the factors that suppress the immune system... We know that stress suppresses the immune system." Dr Ghoneum explains further: "I couldn't believe the evidence of my own eyes when I first saw the effect of ImunoBran. Here was a substance that substantially affects immune function, notably the activity of natural killer cells... ImunoBran has very high safety levels, on par with foods consumed in an ordinary diet. It has no side effects."
This remarkable effect of ImunoBran on NK cells is due to its ability to increase NK-cell activity (rather than numbers of NK cells). This makes them much more effective fighters. The actual process by which their activity is increased is not well-understood, but this stimulatory effect targets only those cells that are sluggish, not cells that are vibrant. This suggests that ImunoBran normalises NK cells activity.
ImunoBran is a functional food, a complex of arabinoxylan compounds and other short-chain polysaccharides derived from rice bran that has been broken down by a specific enzyme from shiitake mushrooms. These unique compounds possess powerful immune-enhancing qualities, strengthening or increasing the activity of weak immune systems. This makes ImunoBran a potent food supplement immunomodulator.
First developed by Daiwa Pharmaceutical in Japan in the 1990s, and now backed by two decades of research (much of it peer-reviewed), ImunoBran is now the supplement of choice for many practitioners and their patients for whom elevating the immune system is a primary concern.
Yasuo Ninomiya, the founder of Daiwa Pharmaceuticals, explains: "We believe that it is of the utmost importance to trust in nature, with which we must coexist. We believe that the body's natural healing power provides the foundation necessary to correct physical imbalances."
ImunoBran is made from insoluble (indigestible) fibre which has then been broken down (or 'pre-digested') in a proprietary process to produce unique soluble compounds with low-molecular-weight, allowing for easy and rapid absorption where it can begin the process of strengthening the immune system.
Research on ImunoBran has been heavily directed to identify and support its anti-tumour and antiviral capabilities; however, it has also been used by doctors to:
- Improve glucose tolerance
- Enhance pancreatic function
- Enhance hepatic (liver) function
- Reduce the adverse effects of chemotherapy
- Improve quality of life
- Neutralise free-radical production.
ImunoBran and COVID-19
Because ImunoBran displays impressive immune defence activity, it may be a useful supplement to take during this time, to help natural recovery and reduction of free radical damage. Research also shows that ImunoBran can support liver function, it is an ideal ally in supporting natural detoxification systems and elimination of toxins, which can greatly reduce the load in circulation and disencumber an already overwhelmed system.
ImunoBran 1000 - 3 sachets dispersed in a little water after a meal for 30 days. Then 1 sachet (or 4 tablets of ImunoBran 250 mg) per day for 2 weeks, or until support is required.
ImunoBran (powder sachets and 250mg tablets) is suitable for vegetarians and vegans. This product is also GMO-free.
Talk to your doctor before taking ImunoBran and do not exceed the recommended dose.
Maucourant, C. et al. (2020). Natural Killer Cell immunotypes related to COVID-19 disease severity. Science Immunology. 5, eabd6832.